Are you looking for painrelief drug? If so Tramadol is the right answer. Tramadol is indicated for treating and preventing pain from moderate to severe, such as acute or chronic pain, and post-surgical pain. Tramadol is a powerful analgesic that works on opiate receptors. Tramadol stereospesific binding receptors in the central nervous system that stopped the sensation of pain and response to pain. In addition, Tramadol inhibits the release of the neutrotransmiter from nerve afferents that is sensitive to stimuli, pain impulses consequently hampered. Although Tramadol interact with the receptor apiat, until now proved incidence after the use of tramadol addiction is low. Just like most analgesic that works in the central, side effects may occur such nausea, vomiting, dyspepsia, obstipasi, fatigue, sedation, dizziness, pruritus, sweating, flushed skin, dry mouth and headache.

In the long-term treatment, the possibility of addiction, therefore doctors must determine the length of treatment. Should not be given any longer than necessary. Just as analgesic drugs, dosage should be regulated according to the severity of pain and clinical response of patients. The use of Tramadol along with drugs acting on the CNS (such as: tranquillizer, hypnotic), can increase the effects of sedation. The use of Tramadol along with tranquillizer can also increase the analgesic effect. In patients with impaired kidney and liver function, dosage adjustments need to be done. Tramadol should not be used in people with drug dependence. Although including opiate agonist, tramadol can not suppress withdrawal symptoms, because giving morphine. Tramadol should not be given to pregnant women unless absolutely necessary.

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